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SLAS2015 Track Descriptions

The SLAS2015 scientific program will feature seven educational tracks. Detailed track descriptions are included below.

If you cannot find your particular topic of interest listed in this below but wish to report on research related to one of the track themes, we encourage you to submit your abstract for consideration by the Program Committee. Individual session titles are listed below, but are subject to change as program development occurs.

The Program Committee will finalize the podium presentation program in September 2014 at which time the presentation schedule and abstracts will be posted within the SLAS2015 Event Scheduler.

Assay Development and Screening

The continued development of novel and more physiologically relevant assay technologies combined with evolving strategies for compound and RNAi library screening seek to broaden both the scope of target classes that can be addressed and to improve HTS success rates. This track will focus on recent innovations across the field including the application of new instrumentation, hardware, and novel assay technologies to compound and/or RNAi library screening. The emphasis will be on case histories where the technology has been developed and implemented in an HTS campaign and the triage process to confirm hits will be described. Sessions include:

  • Biochemical and Biophysical Methods in Screening
  • The Importance of Medicinal Chemistry in Screening
  • Assay Platforms for Biologics
  • Emerging Trends in High Content Screening
  • Natural Products in Screening
  • Cell Based Assays and Screening

Automation & High Throughput Technologies

This track focuses on the innovative tools, technologies, and techniques that enable the advancement of laboratory processes or improve the quality and impact of experimental data for drug discovery and translational research. Emphasis is placed on advancements in engineering, analytical, informatics, and biological technologies and their application to cutting edge automation-assisted research. Sessions include:

  • Non-Traditional Automated Technologies for HTS-ie Label Free Fragment Based Screening
  • Emerging Approaches to High-throughput Screening of Membrane Bound Targets
  • Automating Phenotypic vs. Target Based Discovery-The past-The present-The future
  • Flow based approaches to high throughput processes
  • Machine-learning advances in the life sciences
  • Advances in high throughput analytics and automation

Bioanalytical Techniques

Characterization of biological systems or quantitative analysis of constituents in biological matrices are critical activities in the health and biopharmaceutical sectors. This track will highlight important developments in bioanalytical technologies, including advances in sampling, separation, and identification techniques, high throughput approaches, molecular and functional imaging, and data analysis. Sessions include:

  • Recent advances in membrane protein characterization
  • Targeted proteomics
  • Advances in analysis in biological matrices
 

Drug Target Strategies

Drug discovery relies on a continually deeper and detailed understanding of the mechanisms underlying disease states. This track will focus on studies aimed at advancing our understanding of traditional and novel approaches to drug targets as well efforts to apply such knowledge to translational medicine. Sessions include:

  • Chemical biology approaches to understanding mechanism of action
  • Physiologically relevant target strategies
  • New approaches for interrogating high value targets
 

Micro/Nano Technologies

This track broadly encompasses new and emerging technologies including microfluidics, microarrays, microreactors, nanodevices, and nanotechnologies with emphasis on methods and materials applicable to high-throughput chemistry, high-content screening, point-of-care diagnostics, biology and clinical analysis. Sessions include:

  • Microphysiological systems
  • Diagnostics and point-of-care microdevices
  • Digital and droplet microfluidics
  • Micro and Nanofluidics for Bioanalytical Systems
  • Overcoming Nanotechnologies Challenges
  • Commericialization strategies for Micro and Nanofluidic Devices

Informatics

Modern life science research laboratories now generate and analyze data from diverse sources, many of which are large in size. Informatics plays a critical role in the warehousing, analysis, visualization and flow of these data throughout organizations and between collaborators. This track will focus on the role of informatics in supporting the new operational challenges, enabling knowledge and data discovery, facilitating collaboration, and improving scientific productivity. Sessions include:

  • Data Analysis Approaches for cellular, phenotypic, and high content screening
  • The Challenges of managing big data and new platforms for quantitating biology
  • Facing the challenges of data quality and reproducability
  • Open and public sources of Data
  • Using mobile, web, and cloud technologies to improve the process and communication of research
  • Enhancing Lab Automation via Software

Biomarker Discovery & Applications

The search is on for biomarkers that will improve decision making in the treatment of disease. Better disease diagnosis, prediction of therapeutic efficacy, and monitoring of response to therapy are key to better outcomes. New approaches and technologies that facilitate the discovery and use of biomarkers will be the focus of this Track. Specific areas of interest will include the application of ‘omics technologies, multiplexed analytical approaches, and high content assays for biomarker discovery and validation. Sessions include:

  • Biomarkers for Personalized Medicine
  • Translational Medicine
  • Biomarker Discovery Technologies